Genetic Testing for Cancer: Who Needs It and How Can It Help? By Dr. M. G. Giriyappagoudar Senior Radiation Oncologist, HCG Cancer Centre, Hubli | North Karnataka
When we hear the word “genetic testing,” many people think: “Does this mean I have cancer?” Not necessarily. Genetic testing can help us understand whether a person has inherited a change in a gene that can increase the risk of developing certain cancers. Only about 5–10% of all cancers are estimated to be caused by inherited harmful genetic changes . Therefore, not everyone needs genetic testing . What is genetic testing for cancer? Our body contains genes that act like instructions for our cells. Sometimes, a person is born with a harmful change in one of these genes. This change may increase the chance of developing certain cancers during life. A genetic test can look for these inherited changes, usually using a blood or saliva sample . This is called germline genetic testing . But there is another type of genetic testing Tumor genetic testing looks at DNA changes inside cancer cells. It is mainly used to help doctors understand the cancer and sometimes select targeted treat...