Vertex Oncology Dr Giri

  The human gut is home to trillions of bacteria, collectively known as the gut microbiome. Emerging research suggests that the gut microbiome plays a crucial role in immune function, inflammation, and even cancer progression. Could there be a link between gut health and multiple myeloma? Let’s explore how your microbiome might impact your cancer journey. Understanding Multiple Myeloma What is multiple myeloma? ●        A type of blood cancer that affects plasma cells in the bone marrow. ●        Leads to weakened immunity, bone damage, and kidney issues. The role of the immune system in myeloma ●        A dysregulated immune system contributes to both the development and progression of the disease. The Gut Microbiome & Its Role in Immunity ●        The gut microbiome influences immune response, inflammation, and metabolism. ●   ...

HOW OBESITY INCREASES CANCER RISK   1) Chronic Inflammation: Obesity leads to chronic inflammation, particularly due to visceral fat around vital organs. This inflammation can promote cancer development by damaging DNA and disrupting normal cell growth. The kynurenine pathway, activated by inflammation, affects metabolism and may contribute to carcinogenesis. 2) Hormonal Imbalance: Excess body fat can disrupt hormone levels, such as insulin and estrogen, which play roles in cell growth and division. Elevated insulin levels can stimulate tumor growth, while increased estrogen levels are linked to endometrial and breast cancers. 3) Immune System Alterations: Obesity can alter the immune environment within tumors, promoting the presence of immunosuppressive cells that help cancer grow and spread. 4) Increased Insulin Levels: Obesity often leads to insulin resistance, causing the body to produce more insulin. High insulin levels promote the growth of tumors, increasing the r...